The Detroit Lions take on the Carolina Panthers in Week 4

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By William Smith • Updated Oct 5, 2026 at 04:30

5 things to watch: Lions at Panthers - Detroit Lions — The Detroit Lions take on the Carolina Panthers in Week 4

The Detroit Lions will face the Carolina Panthers in Week 4 on Sunday Night Football. The Panthers seek to enhance their run game against the Lions, while the Lions have updated their depth chart. Fans and analysts are watching key aspects of the matchup, including betting tips and predictions. The Panthers hope to get their run game going against the Lions, while the Lions have revised their depth chart for the game.

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